Fig 1: Representative images of Western blots of ECE1, ET-1, ETAR and ETBR protein expression (left panel) and the corresponding quantitation (right panel) in the control, sham and RDN groups. Data are expressed as the mean ± standard deviation. *p < 0.05, **p < 0.01, ***p < 0.001 vs. sham group; n = 5 per group. Abbreviations: RDN, renal denervation; ET-1, endothelin-1; ETAR, endothelin A receptor; ETBR, endothelin B receptor; ECE 1, endothelin converting enzyme 1; GAPDH, glyceraldehyde phosphate dehydrogenase